Lonza

Research Associate Biochemistry – Lonza – Oss

Jobid=622441838020340471 (0.0988)

Research Associate Biochemistry

Location: Oss

Primeobjectiveof the ADS-R&D Bioconjugates Research function (Oss) is to provide best-in-class targeted delivery technologies,development of protein conjugation technologies,linkersand payloads. General focus is on cytotoxicADCs,howeverother modalities to beemployed inindications such as immuno-oncology, targeted gene therapy, neuromuscular disease, neurodegenerationare also being pursued.

AResearchAssociateBiochemistrysupports the ADS R&D agenda in the field of bioconjugation by contributing to theexecution,and documentation of bioconjugation activities. In this role, the Research Associate performs a wide range of experimental tasks, ensuring high‑quality and reproducible results. They are proficient in applying the full spectrum of analytical techniques available in the laboratory and use these methods to characterize proteins and protein conjugates. The Research Associatemaintainsaccurateand comprehensive experimental records, actively contributes to project progression, and works closely with (senior) scientists.

Whatyouwillget:

  • An agile career and dynamic working culture.

  • An inclusive and ethical workplace.

  • Compensation programs that recognize high performance.

  • A variety of benefits dependent onroleand location.

  • The full list of our global benefits can be found here: .

    The full-time annual base pay for this position in The Netherlands is expected to range between 41.250 EUR MIN and 57.750 EUR MAX.Initialsalary placement within this range will bedeterminedbased on role‑related factors such as experience, qualifications, and expected contribution.

    Whatyouwilldo:

  • Performs experiments as described in protocols.

  • Performs enzymatic and chemical reactions on antibodies and other proteins. Reflects on the outcome of the experiments and discusses the results with their supervisor and proposes next steps.

  • Purifies antibodies and other proteins using a FPLC system and laboratory techniques such as protein A chromatography,SECand IEX.

  • Characterizes antibodies and other proteins using laboratory techniques and equipment such as SDS-PAGE, RP‑UPLC, SE-UPLC, UPLC‑MS.

  • Performs functional analyses including cell-based assays (in vitro cytotoxicity, reporter cell lines) and ELISA-based assays.

  • Maintains high experimental standards through strong attention to detail.

  • Documents procedures,resultsand conclusionstimelyand accurately in Electronic Lab Notebooks (ELN). Review and approve ELN experiments from colleagues to guarantee accuracy and consistency.

  • Handles hazardous and toxic materials responsibly while ensuring safe and compliant laboratory practices and adheres to safety and compliance guidelines.

  • Supportsadditionaltasks (maintainingequipment,coordinatemaintenance with suppliers,manageinventory, ordering) as assigned andcontributesto an efficient laboratory environment.

  • Provides weekly updatesinthe Biochemistry Team meeting.

  • What we are looking for

  • BSc/MSc degree in biochemistry,molecular biology,chemicalbiologyor related field

  • Possesses knowledge on bioconjugation, protein purification andproteincharacterization

  • Has experience withproteinpurification techniques (ProtA, SEC, IEX) and analytical techniques (SDS-PAGE, RP-UPLC,SE-UPLC, UPLC‑MS)

  • Shows strong commitment to laboratory work and task delivery

  • Communicates clearly in English both verbal and in writing

  • Acts as a strong team-player anddemonstratesexcellent time-management skills

  • Has a responsible, conscientious, and sociable character

  • About Lonza

    Synaffixis a biotech company with a clinical-stage platform technology that enables best-in-class antibody-drug conjugates (ADCs), bispecificantibodiesand other targeted therapeutics under a technology out-licensing business model.Synaffixwas fullyacquiredby Lonza in June 2023. Aimed at enabling innovative medicines for patients in areas of high unmet medical need,Synaffixhas forged a growing number of collaborations with top tier biotech and pharma companies by enabling best-in-class therapeutic candidates for their pipelines.

    AtLonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence,Passionand Integrity reflect who we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, andthat’sthe kind of work we want you to be part of.

    Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we value diversity and are committed to creating an inclusive environment for all employees. Ifyou’reready to help turn our customers’ breakthrough ideas intoviabletherapies, we look forward to welcoming you on board.

    Ready to shape the future of life sciences?Applynow.

    Reference: R76582

    Lees hier meer

    Deel deze vacature:

    Deel deze vacature: